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Cholesterol, a complex alcohol constituent of all animal fats and oils. Persons who have abnormally high levels of cholesterol — especially low-density cholesterol — on a congenital basis can reduce their risk of heart attack by lowering their blood cholesterol. There are some effective drugs for weight loss, fat burning, treatment of obesity. Persons who have abnormally high levels of cholesterol—especially low-density cholesterol—on a congenital basis can reduce their risk of heart attack by lowering their blood cholesterol.

Weight-loss medications of any type are only appropriate for people with a BMI of 30 or above, or a BMI of 27 or above accompanied by weight-related medical conditions such as diabetes mellitus or hypertension. Amphetamine drugs were formerly prescribed to combat obesity, but their well-documented side effects, including insomnia, anxiety, and tolerance (the need to take higher and higher doses to continue to produce the same effect), made them less popular by the late 1970s.

Weight loss is a reduction of the total body mass. Intentional weight loss refers to the loss of total body mass in an effort to improve fitness and health. Weight loss occurs when the body is consuming more energy (in work and metabolism) than it is gaining (from food or other nutritional supplements), it will use stored reserves from fat or muscle, leading to weight loss.

A renewed scientific and commercial interest in weight-loss medications was prompted by the approval by the Food and Drug Administration (FDA) of the appetite suppressant.

The FDA has approved orlistat, for long-term use in the treatment of obesity. Some drugs work by blocking the absorption of fat. Scientists are also investigating the hormone leptin, which plays a role in obesity in mice, as a possible treatment for obesity in humans.

There are many diet plans and recipes that can be helpful for weight loss. The most successful diets are those that simultaneously promote physical activity. Other ways of weight loss include use of drugs and supplements in order to decrease appetite and block fat absorption. Nutritionists suggest that a minimum of 1,200 daily calories should be consumed by women in order to maintain health. The daily calorie consumption by men could approach 1,500 daily calories.

Anti-obesity medication or weight loss drugs refer to all pharmacological agents that reduce or control weight. Over a six-month period, weight-loss medications may result in a 10-percent body weight reduction. Weight loss slows or stops after six months, and discontinuing medication usually causes weight regain. The continued use of medications keeps most of the lost weight from returning for two years. Many experts recommend that medications for weight control be used continuously, like medications for diabetes mellitus and hypertension. Unfortunately, few studies have examined the consequences of long-term use of weight-control medications. The main weight loss rule is to avoid foods that are high in fats and sugars.

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